Ulcerative colitis is a chronic disease of the large intestine. It is an inflammatory bowel disease that causes ulcers in the lining of the rectum and colon and its presence increases the risk of colon cancer. Ulcerative colitis is caused due to an abnormal response by your body's immune system.
Ulcerative colitis can happen at any age, but it usually starts between the ages of 15 and 30. Children with the disease may have growth problems. It tends to be hereditary. Ulcerative Colitis is thought to be an autoimmune disease, but it is strongly linked to a poor diet. Stress and antibiotics are often contributory factors.
Functional food for Ulcerative colitis
Extra virgin olive oil (EVOO) is the most effective natural supplement for Ulcerative Colitis. It naturally contains minor constituents such as polyphenolic compounds which have shown a broad spectrum of bioactive properties, including anti-inflammatory, antioxidant, antimicrobial, antiproliferative, antiarrhythmic, platelet antiagregant and vasodilatory effects.
Dietary EVOO have shown to significantly reduce macroscopic and histological signs of damage caused by Ulcerative Colitis and significantly reduced the reduced disease activity.
The body produces nitric acid with the help of an enzyme called iNOS (Nitric Oxide Synthase). This enzyme is usually expressed during inflammatory reactions, as in case of Ulcerative colitis. EVOO and its polyphenolic compounds help in significantly down regulating the expression of this enzyme, thereby controlling pro-inflammatory genes, preventing macrophage activation and protecting the mucosal tissue.